Search results for "Non steroidal"
showing 8 items of 8 documents
Safety of eterocoxib in subjects with histoty of adverse cutaneous reactions to ASA and/or non steroidal anti-inflammatory drugs
2008
Helicobacter pylori eradication in long-term users of non-steroidal anti-inflammatory drugs
1998
P4–286: Secretion of the soluble APP ectodomain (APPS) is not affected by the non–steroidal anti–inflammatory drugs ibuprofen and indomethacin in pri…
2006
ChemInform Abstract: Non-Steroidal Antiinflammatory Agents. Part 23. Synthesis and Pharmacological Activity of Enaminones which Inhibit Both Bovine C…
2010
ChemInform Abstract: Non-Steroidal Antiinflammatory Agents. Part 19. E-2-Pyrrolizin-5-yl Acrylic Acids as Potent Dual or Selective Inhibitors of Bovi…
2010
Non-steroidal anti-inflammatory agents. Part 23. Synthesis and Pharmacological Activity of Enaminones which inhibit both bovine cyclooxygenase and 5-…
1998
The synthesis and stereochemical characteristics of pyrrolidino-, isoquinolino- and indolo-enaminones 2–11 are reported. The inhibition of cyclooxygenase was determined in a bovine thrombocyte intact cell assay and that of 5-lipoxygenase using intact bovine polymorphonuclear leucocytes. Except compound 2c′ which is a well-balanced dual inhibitor of both enzymes, all other enaminone derivatives are weak inhibitors of both cyclooxygenase and 5-lipoxygenase. Structure-activity relationships of the enaminones in relation to known anti-inflammatory drugs are discussed.